Translation of "Schwerwiegende bedenken" in English

The ECB has serious concerns as to the appropriateness of the proposed procedure .

But alongside those strong grounds for optimism are significant worries.

From this point of view we have substantial reservations about distillation.

Obesity is a serious health problem and should be addressed.

The Committee has serious reservations about the provisions on expropriation and compensation.

In conclusion, I would like to say that my group has very serious objections to this proposal.

Yet there is still no agreement on this and I have grave concerns in respect of future presidencies, notably Hungary and Poland, since regulation does not seem to be one of their priorities.

On this particular application from Novartis for the maize, especially strong objections were raised in Member States and within the European Parliament.

The reality is that the United States has serious concerns and constraints which it is discussing with the large emerging economies.

We have very grave reservations, especially concerning Amendment No 4, which drops the retention provision, and Amendment No 5, which extends the expiry date to 20 years.

I had serious concerns about full cabotage delivered in one move without any levelling-up of social costs, or indeed running costs, for individual hauliers.

I also have grave concerns about reverse qualified majority voting in Council decisions linked to these reports.

Even though I voted in favour, I voted with grave and serious reservations.

There is huge concern about the balance between security and civil liberties being tipped too far towards security in the United States.

I also have grave reservations about the sweeping provisions suggested for Members' immunity.

During the assessment of the periodic safety update report (PSUSA) for Lemtrada (EMEA/H/C/PSUSA/00010055/201809), the following new emerging and serious safety concerns were highlighted in addition to the known safety profile of alemtuzumab, which raised major concerns to the Pharmacovigilance Risk Assessment Committee (PRAC):

In view of (a) the evidence suggesting that linear GdCAs release Gd from their chelating ligand molecules due to the low kinetic and thermodynamic stability; (b) the known toxicity of unchelated gadolinium; (c) the data supporting the ability of linear GdCAs to distribute and accumulate in the brain; (d) the fact that linear agents are retained and persist for up to one year or longer in the brain; and (e) the deposition in other tissues with related harm; PRAC considered that there are reasonable and serious concerns raised as to the potential of neurological harm associated with the accumulation of gadolinium in the brain.

Why is this menace a matter of grave concern in Japan today, and a threat worth worrying about in the US?

Nevertheless, as pointed out by some members of the CVMP, serious disadvantages persist in terms of hygiene and the possibility of secondary infections, particularly if BST is to be used in farming and not in an optimal, experimental environment.

The Committee has serious objections to the arrangements proposed in Annex IV as these rely too heavily on good organization by manufacturers and do not provide for any effective control by a third party.

The examination of an application should be accelerated and completed within a maximum of two months in those instances where an application is manifestly unfounded because it is an abusive claim, including where an applicant comes from a safe country of origin or an applicant is making an application merely to delay or frustrate the enforcement of a removal decision, or where there are serious national security or public concerns, where the applicant does not apply for international protection in the first Member State of entry or in the Member State of legal residence or where an applicant whose application is under examination and who made an application in another Member State or who is on the territory of another Member State without a residence document is taken back under the Dublin Regulation.

A review of the situation of the AOCs and attached operations specifications of the air carriers Aero Benin, Africa Airways, Benin Golf Air, Benin Littoral Airways, Cotair, Royal Air and Trans Air Benin reveals serious concerns.

The Commission, having regard to the above mentioned situation, has entered into consultation with the competent authorities of Sao Tome and Principe, expressing serious concerns about the safety of the operations of Executive Jet Services, STP Airways, as well as about the relocation to the register of Sao Tome of aircraft used by air carriers currently subject to an operating ban within the Community and asking for clarification regarding the actions undertaken by the competent authorities to respond to these concerns.