Translation of "Grosstechnischen massstab" in English

Troublefree operation of this process, particularly on an industrial scale, is not possible.

The EBA technology is scalable to the large technical scale and does not require complex apparatus technology.

In addition, adhering to the proposed forms, cost-effective production on an industrial scale is scarcely possible.

All the above processes are unsatisfactory in respect of yield, easy availability of the starting materials, purity and range of the end products obtainable, simplicity and economy of operation, and non-pollution of the environment, particularly when operated on an industrial scale.

All these processes are unsatisfactory in respect of optimum yield and purity of the end product coupled with simple, safe and economical operation, particularly on an industrial scale.

Both processes require an exceptional degree of technical effort and proceed with unsatisfactory yields and are thus unsuitable for application on a large industrial scale.

Appropriate spot fusion can be realized on a technically large scale by using a heated calender, the cylinders of which have suitable surface engraving.

On a large scale, mixing is intended to be effected in horizontal signal-type kneaders of the kind which is usual in processing bitumen.

In the sulfoxidation process as it is carried out on a large industrial scale (Chemie in unserer Zeit, 13 (1979), page 161), the product phase is concentrated in vacuo, without the addition of solvents, and water is removed by distillation together with a part of the paraffin.

From the faults, which cannot be avoided completely in insulation produced on a large technical scale, the tree-like structures extend in the direction of the electric field.

In order to fulfil the required purity criteria, a recrystallisation step (from petroleum ether), which is particularly expensive on a large industrial scale, must be included after the vacuum distillation of the end product.

Thus the reaction can be carried out at much more reasonable cost and more reliably, and it is now also suitable for use on a large industrial scale.

Compared to the conventional process, the process according to the invention surprisingly gives a large number of aliphatic isocyanates more simply and more economically, in substantially better yield, better space-time yield and greater purity, and in particular does so when operated on an industrial scale and by a continuous method.

This condensation is preferably carried out in chlorinated solvents, in particular in o-dichlorobenzene, as is in general also done on a large industrial scale.

However, the use of solvents on the industrial scale is nowadays avoided wherever possible for environmental and economic reasons, so that methods for the solvent-free preparation of nitriles are desirable.

Thereby, a longer use of the chromatography columns can be obtained, for which reason the method is also particularly suitable for use in a large technical scale.

But, especially in view of the very expensive cleansing of the end product, the production of this product for use as additive to fish feed on a big industrial scale by the known process is not feasible because it is much too unprofitable.

An especially suitable process, which can be carried out profitably on a large industrial scale, consists of adding chlorosulfonic acid to the solution containing trimethylamine and conducting gaseous ammonia through this reaction mixture in order to recover amine from the amine hydrochloride resulting first as a by-product.

There is therefore a need for an inexpensive process for the preparation of 2-alkoxybenzosulfonamides, which process can be carried out on a large industrial scale.

The process is particularly suitable for industrial use and for continuous operation, presents no significant effluent problems and is ecologically more advantageous than the conventional processes.

Another surprising advantage is that the sugar esters of the invention are readily and easily produced on a large scale.

When manufacturing powdery or granular detergents and cleaners to be used for large scale production type spray drying processes, the process starts with an aqueous slurry which incorporates most or even all of the detergent constituents.

The known processes have, however, considerable disadvantages which make it considerably more difficult to convert them to the large industrial scale.

The flagship plant testifies to the competitive viability and sustainability of the sunliquid technology on an industrial scale, and at the same time fulfils an important function as a reference facility for the worldwide marketing of sunliquid licenses.

Such supercooled liquids are produced on a large industrial scale when atmospheric air is split into its components by cooling and cleaning or, in the case of hydrogen, water is split into its components.

Today, the use of dimethylformamide on a large industrial scale is to be avoided wherever possible owing to toxicological and environmental considerations.

While transferring and optimizing research production processes for industrial scale use and developing high-throughput fermentation and purification processes are governed by certain rules, they differ for each antibody, calling for great expertise in process development and process data management.

If 2,4-dichloroacetophenone-oxime-O-benzyl-ether and bromine are used, the reaction can be represented by the following equation: ##STR3## Compared to the prior art, the process according to the invention surprisingly gives a-bromoacetophenone-oxime-ethers more simply and more economically, in better yield, higher space-time yield and greater purity, in particular on an industrial scale and in continuous operation.

The object of the invention is to provide a simple process, feasible on a large scale, for the production of gamma-butyrobetaine from butyrolactone, which provides good yields and is quite safe from the ecological aspect.