Übersetzung für "Reaction vial" in Deutsch

Mix completely by coating the entire inner surface of the reaction vial.

Gently add the formulation buffer down the side of the reaction vial.

Using a 1-ml sterile syringe, transfer sodium acetate solution to reaction vial.

In one embodiment of the invention, the reaction vial contains:

Additionally provided in the reaction vial may be lyophilized ascorbic acid or another suitable stabilizer.

The mixture in the reaction vial 3 has been lyophilized.

The kit contains one ibritumomab tiuxetan vial, one sodium acetate vial, one formulation buffer vial, and one empty reaction vial.

The preferably lyophilized mixture in the reaction vial is dissolved with the solvent from the solution vial.

The SCX cartridge is then eluted, using the solution from the elution vial, into the reaction vial.

The lyophilized mixture in the reaction vial 3 is dissolved with the solvent from the solution vial 4 .

Immediately prior to this addition withdraw an equal volume of air from the reaction vial in order to normalise pressure.

Aseptically transfer 1500 MBq of yttrium-90 chloride with a 1 ml sterile syringe to the reaction vial containing the sodium acetate solution transferred in step 1.

The reaction solution which is produced in the reaction vial 3 may optionally be heated at 90° C. to 100° C., over a time of 5 minutes to 15 minutes, for example, more particularly seven minutes, in order to accelerate the reaction, in which the 68 gallium joins with the labeling precursor to form the radiopharmaceutical 8, also called tracer.

The reaction solution which is produced in the reaction vial may optionally be heated at 90° C. to 100° C., over a time of 5 minutes to 15 minutes, for example, more particularly seven minutes, in order to accelerate the reaction, in which the 68 gallium joins with the labeling precursor to form the tracer.

In one embodiment of the invention, the reaction vial contains a lyophilized mixture of sodium acetate and a ligand-conjugated peptide, as for example DOTA-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) or NODAGA-conjugated peptide, more particularly DOTATOC (edotreotide) or DOTATATE (DOTA-[Tyr 3]octreotate).

The labeling precursor present in the reaction vial 3 is a DOTA- or NODAGA-conjugated peptide, more particularly DOTATOC or DOTATATE.

The cation exchange cartridge 2 is then eluted by means of the solution from the elution vial 5 into the reaction vial 3 .

Sample liquids are provided in receptacles 1 which, in the shown illustrative embodiments, are commercial reaction vials made of thin-walled plastic.

For that purpose, the sample liquids are present in vials 1 which in the embodiment shown are commercial thin-walled plastic reaction vials.

Further improvements include a reinforced housing, optimized liquid nitrogen duct and new accessories such as an adapter for 6 reaction vials and a 10 ml grinding jar.

The invention is applicable in particular for increasing the robustness and reliability of optical measurements, used for process monitoring of the culturing of cells and also chemical reactions, on continuously mixed reactors, in particular shake flasks, microtiter plates, stirred tank fermenters, and reaction vials.

In agitated reactors, in particular in shake flasks, shake bottles, fermentation bags, reaction vials, and microtiter plates, the form and distribution of the reactor content changes continuously, thus making optical measurements more difficult.