Translation of "Stufenweise umsetzung" in English

In the preferred embodiments of the process the reaction is carried out in steps. Process (a)

The stepwise implementation of the different REACH obligations will also extend into the following years.

A process as claimed in claim 1, wherein the reaction is carried out stepwise or continuously.

This step-wise reaction can also be carried out in three or more stages using increasing amounts of catalyst in each stage.

That is why we sought to provide for a phased implementation that is carefully adapted to circumstances.

Monitoring of implementation and enforcement will be continued with particular attention on those areas where transitional arrangements providing for gradual implementation of a limited number of EU Directives have been agreed with these countries.

The Commission, therefore, proposes a step-by-step approach to implementation, to be accompanied by an advisory committee from Member States experts and with the full involvement of all stakeholders.

It allows a staggered implementation so that existing implementing legislation that complements Regulation (EC) No 2320/2002 can be updated by Committee procedure to bring it into line with the new act so as to avoid a lacuna when the existing Regulation would be repealed.

Fourth, if adapting or gradual (transitional) application of the Community policy in one or more regions is not feasible or not considered effective, or jeopardises the expected benefits of the Community policy for the EU as a whole, then decide to implement complementary policies in specific regions (including policies of a structural nature), so as to eliminate, or mitigate the negative effects for cohesion in these regions.

The derivatives are prepared by stepwise reaction of cyanuric chloride with the corresponding YH, Y'H and Y"H compounds.

They can be prepared by stepwise reaction of cyanuric chloride with the compounds R1 -X'-Y'H and R2 -X"-Y"H and a 4-hydroxy- or 4-amino-polyalkylpiperidine.

The reaction is preferably carried out in steps by initially reacting the diol with excess diisocyanate and then reacting the monoalcohol.

In another embodiment of the invention, the reaction may proceed step-wise via a prepolymer process, wherein, for example, an NCO prepolymer is initially prepared from components I) and II). This prepolymer is then reacted with component IV) in the presence of component III).

A process as claimed in claim 1, wherein the reaction is carried out stepwise or continuously, and the formamide (IV) is loaded with from 0.1 to 95 mol % of phosgene.

The starting compounds of formula II are prepared in conventional manner by stepwise reaction of cyanuric chloride with the corresponding amines in a water-immiscible solvent, preferably toluene, in the presence of an aqueous solution of a base.

The 1,2-disulfonylhydrazine compounds to be used as starting substances are accessible in a simple manner by known methods, e.g., by the reaction of hydrazine with corresponding sulfonyl chlorides. It is also possible to obtain the unsymmetric 1,2-disulfonylhydrazine compounds by a stepwise reaction.

The preparation of unsymmetrical tetra-substituted ureas from a secondary amine A by stepwise reaction with phosgene and a secondary amine B is known per se, and it is also known that such a reaction is carried out in an inert solvent and in the presence of a stoichiometric amount of an HCl-bonding base.

A dyebath is prepared, containing, in 1,000 parts by volume, 10 parts of the dyestuff of the formula (written as the free acid) ##STR43## preferably as sodium salt (prepared by subjecting copper phthalocyaninetetrasulfochloride to a condensation reaction with 3-?-sulfatoethylsulfonylaniline and 1,3-diaminobenzene-4-sulfonic acid and subsequently reacting the reaction product stagewise with cyanuric fluoride and aniline-3-sulfonic acid), 75 parts of sodium sulfate, 7 parts of sodium carbonate and 16 parts by volume of 2N sodium hydroxide solution.

For the preparation of the organopolysiloxane-ammonium compounds, which contain multiple complex anions of platinum and/or palladium, the conversion of the platinum and/or palladium starting materials with the organopolysiloxane-ammonium compound of formula (1) wherein Yx- is a 1 to 3 valent anion of an inorganic or organic protonic acid can be carried out simultaneously or in a stepwise manner, wherein the ultimately obtained metal containing solid material can be separated from the liquid phase, washed, and dried, optionally after each conversion and in any desired reaction sequence and, if desired, optionally tempered.

European Patent 225 826 discloses the preparation of ethylenically unsaturated, fluorine-containing bisurethanes which can be obtained by stepwise reaction of, firstly, an isocyanate group of toluylene diisocyanate with a fluoroalkanol and then of the other isocyanate group with a hydroxyalkyl (meth)acrylate.

This prepolymer can be prepared, for example, by reaction of durene diisocyanate with at least one higher molecular weight polyhydroxy compound a) or a mixture of a) and at least one chain-lengthening agent and/or at least one crosslinking agent c) or by stepwise reaction of durene diisocyanate with at least one higher molecular weight polyhydroxy compound a) and then with at least one chain-lengthening and/or crosslinking agent.

It has now been found that the foregoing object is achieved by a process for the preparation of optionally copolymeric polypeptides by simultaneous or stepwise reaction of glutamic acid and at least one further a-amino acid and/or derivatives thereof with amines in the absence of solvents and catalysts under condensation conditions, optionally at subatmospheric pressure and with removal of the condensate from the reaction mixture.