Translation of "Sensibilisierende stoffe" in English

We expressly reject the following suggestions made by the rapporteur of the Committee on the Environment, Public Health and Consumer Policy: that sensitising substances be included in the approval procedure; that approval be granted only for a limited period; that the registration requirement should apply to all amounts under one tonne; that the public be given unrestricted access to all data; that there should be extensive prohibitions on materials; that extensive data and evaluations to be submitted by the industry should be subject to additional examination by peer review; and a number of other points.

In order to better inform the consumer about possible adverse effects of hair dye use and to lower the risk of sensitisation to hair dye products among consumers, appropriate warnings should be printed on the label of oxidative hair dye products and of non-oxidative hair dye products containing hair dye substances with an extreme or strong sensitising potential.

The basic principle underlying the LLNA is that sensitisers induce proliferation of lymphocytes in the lymph nodes draining the site of test substance application.

The basic principle underlying the LLNA: BrdU-ELISA is that sensitisers induce proliferation of lymphocytes in the lymph nodes draining the site of test substance application.

The basic principle underlying the LLNA is that sensitisers induce a primary proliferation of lymphocytes in the lymph node draining the site of chemical application.

In order to better inform the consumer about the possible adverse effects of hair colouring and to lower the risk of sensitisation to hair dye products among consumers, additional warnings should be printed on the label of oxidative hair dye products and of certain non-oxidative hair dye products containing extreme and strong sensitising substances.

In addition some chemicals that are harmful to theskin, such as irritants and sensitisers, are not even provided with askin notation.

The sensitizing potential of these substances was not included in the evaluation, since dermatologists have established that this effect is rarely observed in practice.

The labelling of compounds which contain very low concentrations of sensitizing substances with a specific classification limit value was modified.

In order to prevent a contact allergy, information is required on the sensitising action of the substances and preparations, and possible exposure.

Owing to the molar mass distribution which results from the prepolymerization reaction, PU-HMs of this kind include significant quantities of unconverted monomeric diisocyanates (“monomers”), which undergo outgassing at the application temperatures customary for hotmelt adhesives, of 85 to 200° C., typically 120 to 160° C., and which may pose a health challenge to the user, being irritant, sensitizing or toxic substances.

Here, based on the implementation of a set of regulations, effective health pedagogic measures, technical rules for sensitizing substances and a substantial renunciation of glycerol monothioglycolate the number of cases and the amount of compensatory damages has been cut in half from 1994 to 1998.

In order to prevent or treat a contact allergy, knowledge is needed about the sensitising effect of the substances and preparations and the type of contact involved.

Hence, the Federal Minister for Work and Social Affairs recommends these professional groups to abide by the technical regulations "TRGS 531 - Risks of skin disorders caused by working in humid conditions" and "TRGS 540 - Sensitizing Substances.

The CLP Regulation also addresses the conditions under which sensitising ingredients can be used. It specifies clear thresholds for the classification and labelling if sensitising substances are contained in candles and provides appropriate infor-mation for the minority group of people who actually are sensitive to certain ingredients whilst allowing the vast majority of people who have no problems to use the products safely.

Exogenous noxae as e.g. sensitizing substances, germs and their metabolism products but also micro-filings may easily penetrate into the skin and cause allergic contact eczema and infections2,3) .

Actually, as couperosis skin is very sensitive and permeable, potentially irritating or sensitizing substances like perfumes and preservatives should definitely be avoided.

Occupational asthma caused by sensitising agents or irritants recognised as such and inherent in the type of work.

Among the last named above all mental stress, climatic conditions, microbial infections as well as irritating and sensitizing substances play a major role.

The list of known sensitisers currently totals more than3500 substances.

Whereas it is necessary, on the basis of scientific and technical research, to draw up proposals for lists of authorized substances which could include antioxidants, hair dyes, preservatives and ultraviolet filters, taking into account in particular the problem of sensitization;

Redundancy in the labelling of mixtures containing isocyanates and certain epoxy constituents should be avoided while maintaining the longstanding and well known specific information about the presence of these particular sensitizing substances.

The proposal requires that the name of certain sensitizing substances present below the classification concentration be however put on the label with the inscription: "Contains name of sensitizing substance.

If, for example, one of the weak sensitisers were misclassified, a rationale for the misclassification and appropriate additional data (e.g. test results that provide correct classifications for other substances with physical, chemical, and sensitising properties similar to those of the misclassified reference chemical) could be considered to demonstrate equivalent performance.

Obligation to label certain sensitizers, even below the general classification limits.

Additional labelling of certain sensitizers: putting the name of certain sensitizing substances on the label to alert sensitized persons is a sensible requirement.

With regard to the use of allergenic substances, the EESC recommends that the Commission prohibit the use of all fragrances and sensitisers, since they may contain not only allergenic substances – that should clearly be banned, even if their use is technically unavoidable in manufacturing the product – but also other substances that could have direct implications for children's immune systems.

With regard to the use of allergenic substances, the EESC recommends that the Commission prohibit the use of all fragrances and sensitisers, since they may contain not only allergenic substances – that should clearly be banned– but also other substances that have direct implications for children's immune systems.