Translation of "Molecular probes" in German

These are concentrating on the use of molecular probes that can be controlled by chemical means.

Alexa Fluor® 532 is a Molecular Probes (Invitrogen) dye, which is not available through our OligoShop.

The oligonucleotide is labeled with Bodipy (Molecular Probes) at the 5?-C 6 position.

Dipicolinic acid (DPA) and 4-pyrene sulfate (4-PS) were obtained from Molecular Probes.

Such molecular probes contain the peptide according to the invention and can be injected in the patient, for example intravenously.

However, studies using molecular probes (DeLong 1998, Curr.

It is an object of the invention to provide novel microsatellite markers for the genetic analysis of plants of the Triticum aestivum species, which markers are distinguished by a degree of DNA polymorphism, which is higher than that of other molecular probes, that have been developed previously for the wheat genome.

Suitable functionalized fluorescent dye residues which can be used as reagents for preparing the compounds according to the invention of the formula I are described, for example, in Handbook of Fluorescent Probes and Research Chemicals, 5th Edition, 1992-1994 by R. P. Haughland, Molecular Probes, Inc.

Subsequently, after labeling the DNA with the sensitive dye SYBR Gold (Molecular Probes) on a 1% agarose gel the protection of the nucleic acids from nuclease breakdown is analyzed (FIG. 5).

Molecular Probes, Inc.) having a spectral shift depending on the ion concentration are used for this purpose.

By measuring the binding of a fluorescent ligand of the beta-adrenergic receptor (BODIPY-TMR-CGP 12177 by Molecular Probes) the successful refolding is shown.

In this FLIPR assay, the influx of Ca 2+ is quantified with the assistance of a Ca 2+ -sensitive dye (type Fluo-4, Molecular Probes Europe BV, Leiden, Netherlands) in a Fluorescent Imaging Plate Reader (FLIPR, Molecular Devices, Sunnyvale, USA) as described below.

According to this assay, the influx of Ca 2+ through the receptor channel is quantified with the assistance of a Ca 2+ -sensitive dye (type Fluo-4, Molecular Probes Europe BV, Leiden, Netherlands) in a Fluorescent Imaging Plate Reader (FLIPR, Molecular Devices, Sunnyvale, USA).

Propidium iodide (PI) (molecular probes, Eugene, Oreg., USA) was added to stain death cells.

This question is what interests the Research Unit "G Protein Signal Cascades: Using New Molecular Probes and Active Substances to Develop New Pharmacological Concepts" .

All that is critically dependent on the development of both highly specific radioactive molecular probes as well as computational methods of image reconstruction and data evaluation.

Vitality of the cultures was measured using the Life- Dead-Assay (Molecular Probes).

According to this assay, the Ca 2+ influx through the channel is quantified with the aid of a Ca 2+ -sensitive dye (type Fluo-4, Molecular Probes Europe BV, Leiden, Netherlands) using a Fluorescent Imaging Plate Reader (FLIPR, Molecular Devices, Sunnyvale, USA).

On the following day, the cells are loaded for 60 minutes at 37° C. with 2.13 ?M Fluo-4 (Molecular Probes Europe BV, Leiden, Netherlands) in HBSS buffer (Hank's buffered saline solution, Gibco Invitrogen GmbH, Karlsruhe, Germany) with 2.5 M probenecid (Sigma-Aldrich, Taufkirchen, Germany) and 10 mM HEPES (Sigma-Aldrich, Taufkirchen, Germany).

According to this assay, the Ca 2+ influx through the receptor channel is quantified with the aid of a Ca 2+ -sensitive dye (Type Fluo-4, Molecular Probes Europe BV, Leiden Netherlands) in a fluorescent imaging plate reader (FLIPR, Molecular Devices, Sunnyvale, USA).

Subsequently, the cells are loaded with 2 ?M Fluo-4 and 0.01% by volume of Pluronic F127 (Molecular Probes Europe BV, Leiden Netherlands) in HBSS buffer (Hank's buffered saline solution, Gibco Invitrogen GmbH, Karlsruhe, Germany) at 37° C. for 30 min, washed 3× with HBSS buffer and, after a further incubation of 15 minutes at room temperature, employed in the FLIPR assay for Ca 2+ measurement.