Translation of "Meaningful change" in German

There was no meaningful change from baseline in body weight in either group.

There was no meaningful change in digoxin Cmax.

Ospemifene did not cause a clinically meaningful change in the exposure to the substrates, indicating that ospemifene does not affect those enzyme activities in vivo to a clinically significant extent.

You've trimmed some of this spending, you've embraced some meaningful change.

They understand that their role is to make the change meaningful and easier to accept.

Meaningful political change can only be ensured if the neoliberal economic policy agenda is thrown out.

This trend confirms a defiant attitude against politics as usual and a desire for meaningful change.

Furthermore, no meaningful change can be achieved without the active involvement and participation of those honest fishermen and women.

The political dialogue will be underpinned by our offer to support pressing institutional reforms in the next aid strategy which, if accepted by the government, would contribute to a meaningful change and thus to more progress and prosperity for the people of Bangladesh.

We can commit these small acts of bravery and hope that our choices trickle upward to the people in power -- editors, movie and music producers, CEOs, lawmakers -- the people who can make bigger, braver choices to create lasting, meaningful change.

Does that mean that the world should not expect meaningful change in Iran’s official behavior following Rowhani’s victory?

This finding, which was reflected across the sizes and major business groups, shows that business is pushing for a "meaningful change" that brings powers back to the UK.

Meaningful change requires not only plans but action, including readiness on the part of able Member States to share information and expertise and to provide adequate logistical and financial resources and ongoing political support.

In patients with mild to moderate hypertension, infusion of 100 mg fosaprepitant over 15 minutes with diltiazem 120 mg 3 times daily, resulted in a 1.4-fold increase in diltiazem AUC and a small but clinically meaningful decrease in blood pressure, but did not result in a clinically meaningful change in heart rate, or PR interval.

Administration of laropiprant 40 mg in non-dialysed patients with severe renal insufficiency resulted in no clinically meaningful change in the AUC and Cmax of laropiprant, compared to healthy control subjects.

Consequently, no meaningful change in AUC of methylnaltrexone bromide, in addition to Cmax, was observed before and after multiple-dose administration of cimetidine.

Overall, severe to moderate renal impairment did not result in a clinically meaningful change in the PK profile or safety of telotristat ethyl and its metabolite telotristat.

In patients with mild to moderate hypertension, infusion of 100 mg of fosaprepitant over 15 minutes with diltiazem 120 mg 3 times daily, resulted in a 1.4-fold increase in diltiazem AUC and a small but clinically meaningful decrease in blood pressure, but did not result in a clinically meaningful change in heart rate, or PR interval.

Patients' physical function, global health status and diarrhoea scores showed a clinically meaningful change during chemotherapy in both treatment arms.

There is therefore no reason to expect that strong CYP3A4 inhibitors would cause a clinically meaningful change in ospemifene exposure.

Co-administration of ixazomib with clarithromycin, a strong CYP3A inhibitor, did not result in a clinically meaningful change in the systemic exposure of ixazomib.

In healthy subjects, oral prednisone (20 mg three times daily for five days) did not produce a clinically meaningful change in oral bioavailability of alendronate (a mean increase ranging from 20% to 44%).