Übersetzung für "Trial population" in Deutsch

HRQoL data could be analysed for a subset of the full trial population.

However, the overall free trial is a population for the population for the population of an aplastic anemia.

Although no clinical data have been generated with Daronrix in subjects > 60 years of age, the immunogenicity of a mock up formulation with different antigen doses of an aluminium-adjuvanted whole virus vaccine (A/ H9N2) administered at 0, 21 days was evaluated in a clinical trial in this population.

A multicenter, randomised, double-blind, placebo-controlled trial (SOLVD Treatment trial) examined a population with symptomatic congestive heart failure due to systolic dysfunction (ejection fraction < 35%).

Table 1 lists adverse reactions identified from an integrated clinical trial population of over 5,000 rosiglitazone-treated patients.

Based on this trial and population pharmacokinetic analysis of data derived from clinical trials in various tumour types, it is concluded, that adjustments to the starting dose in patients with mild (eGFR 60-89 mL/min/1.73m²), moderate (eGFR 30-59 mL/min/1.73m²), or severe (eGFR 15-29 mL/min/1.73m²) renal impairment are not necessary, but patients with severe impairment should be monitored (see “Population pharmacokinetic analysis in special populations” below and section 4.2).

Although no clinical data have been generated with Daronrix in subjects > 60 years of age, the immunogenicity of a mock up formulation with different antigen doses of an aluminium-adjuvanted whole virus vaccine (A/H9N2) administered at 0, 21 days was evaluated in a clinical trial in this population.

Kite (+75% in USD during 1Q 2017) released positive topline results from their complete pivotal trial population given KTE-019 to treat relapsed/refractory diffuse large B cell lymphoma (DLBCL).

We look forward to seeing what this IL-17C mechanism of action can bring to a larger trial population for longer treatment duration," said Dr. Piet Wigerinck, Chief Scientific Officer of Galapagos.

Additional new data for various triple combination treatments (Kalydeco, Orkambi and VX-661 together) are eagerly anticipated in the second half of 2017. Kite (+75% in USD during 1Q 2017) released positive topline results from their complete pivotal trial population given KTE-019 to treat relapsed/refractory diffuse large B cell lymphoma (DLBCL).

Additional efficacy data are available from 3 single-arm Phase II trials with similar populations treated with the same regimen.

Furthermore, it was noted by the CHMP that, despite the limited sample size in the clinical trials, this patient population cannot be considered as a ‘small population' as defined by the EMA Guideline on Clinical Trials in Small Populations (CHMP/EWP/83561/2005).

Superiority (2 trials) or non-inferiority (4 trials) has been shown in six out of seven efficacy trials in heterogeneous populations of depressed adult patients versus SSRI/SNRI (sertraline, escitalopram, fluoxetine, venlafaxine or duloxetine) The anti-depressive effect was assessed with the HAMD-17 score either as primary or secondary endpoint.

Additional efficacy data are available from 3 single-arm Phase II trials with similar populations treated with the same regime.

The pharmacokinetics of Caelyx was evaluated in 120 patients from 10 different clinical trials using the population pharmacokinetic approach.

The safety and efficacy of Xultophy were evaluated in seven randomised, controlled, parallel group phase 3 trials in different populations of subjects with type 2 diabetes defined by previous antidiabetes treatment.

Mixed- population trials: Six months or more after the beginning of the trial, people receiving incentives were more likely to have quit than those in the control groups.

Mixed- population trials: We found 21 trials, covering more than 8400 people, which looked at different incentive schemes to help smokers to try and quit.