Übersetzung für "Schnell freisetzende" in Englisch

For forms with very rapid release, this technology has therefore reached its limits.

After drying of this layer the readily soluble or rapidly releasing film layer is applied thereto.

The rapid release layer additionally comprises one or more disintegrants, one disintegrant is preferred.

As Example 1, but a rapidly releasing initial dose of 10 mg of nifedipine in a mixture of auxiliaries customarily used for film lacquering (hydroxypropylmethylcellulose HPMC, PEG 4000) is applied to the press-coated tablet.

If it is wished to produce solid drug forms with rapid release, it is necessary to use ancillary substances which have a high rate of dissolution in accordance with correspondingly high solubility in water and which, moreover, must not adversely affect the melt-processability of the polymer melt containing active ingredients.

Good tolerability, the absence of sedative effects and the instant release formulation (administered just three times daily) will significantly improve patients' quality of life.

The process according to claim 1, wherein the resulting pharmaceutical composition is a tablet rapidly releasing the active compound (I).

Release of active ingredient can be speeded up appropriately by additions of water-soluble substances, in particular of water-soluble polymers, so that it is also possible to form rapid-release coatings or coatings for taste masking.

The rapid release dosage form according to the invention is particularly suitable for impeding or preventing the abuse of at least one pharmaceutical active substance with abuse potential, selected from the group including opioids, tranquillisers, preferably benzodiazepine, barbiturates, stimulants and other narcotics, in particular active substances with a psychotropic effect.

BACKGROUND OF THE DISCLOSURE For high efficacy and bioavailability of pharmaceuticals, it may be necessary to reach high serum levels of active substances in a very short time, which requires dosage forms that are released as quickly as possible.

The crystalline microparticles of active substance and the solid form of particles of active substance of the present invention are therefore especially suitable for fast release and in particular very fast release dosage forms.

Such a pharmaceutical formulation may be conventional but may also be arranged as a fast-releasing or retarding formulation dependent upon the special requirements of the patient.

Tramadol is preferably used in excess for the in situ reaction with diclofenac so that, in these formulation, an initial dose of tramadol is released rapidly and afterwards tramadol and diclofenac undergo retarded release at the same rate.

The second (water-soluble, rapidly releasing) film can be formulated for example by partially hydrolyzed polyvinyl alcohol, which is layered onto the heat-treated (initial) film.

Sanochemia filed registration dossiers for its instant release formulation in Germany andSwitzerland in December 2004 and May 2005, respectively.

Good tolerability, the absence of sedative effects and the instant release formulation (administered just three times daily) will significantly improve patients’ quality of life.

This precision protein blend contains rapid-releasing whey and slower digesting micellar caseins from milk protein isolate/concentrate plus calcium and sodium caseinates.

So, then, what might occur if we release gas too quickly?

In a preferred fashion, such tablets are suitable for rapid release of the active substance.

A steep gradient is interpreted to be synonymous with rapid release of the antiperspirant active ingredient.

WO 97/22619 also describes a standard table for rapid release of the prodrug.

The interaction with water occurs quite rapidly, with the release of heat and the formation of an alkaline solution.

Up to now there were no adverse events potentially related to a faster release of doxazosin reported.