Übersetzung für "Cumulative exposure" in Deutsch

Total cumulative exposure of daunorubicin has been described in the table below.

The incidence and severity of lipoatrophy are related to cumulative exposure.

In addition, the cumulative exposure to more than one active substance shall, where relevant, be considered.

Xofigo contributes to your overall long-term cumulative radiation exposure.

Xofigo contributes to a patient’s overall long-term cumulative radiation exposure.

Therefore, long-term cumulative radiation exposure may be associated with an increased risk of cancer and hereditary defects.

Long-term cumulative radiation exposure may be associated with an increased risk of cancer and hereditary defects.

If this period is doubled, the risk is also doubled for the same cumulative exposure.

The veins occur in association with rosacea, cumulative sun exposure, and the passage of time.

However, the approach is not suitable for determining the chronic cumulative exposure of consumers to active substance residues from different plant protection products.

There is evidence that higher dose and/or cumulative exposure are risk factors for development of valvular pathology.

The cumulative median duration exposure to Votubia (361 patients who took at least one dose of everolimus) was 30.4 months (range 0.5 to 48.8).

Repeated MUGA scan or ECHO determinations of LVEF should be considered in patients with risk factors such as high cumulative exposure to prior anthracyclines or significant pre-existing cardiac disease.

In order to minimise the risks, the MAH has proposed to eliminate all indications that require prolonged treatment at higher dosages, e.g., systemic mycoses requiring treatment for 6 months or longer, taking into account that hepatotoxicity has usually been reported after extensive cumulative exposure to ketoconazole, and to limit indications to Malassezia folliculitis, Tinea capitis and chronic mucocutaneous candidiasis in patients who had either developed intolerance or failed to respond to alternative oral and/or IV antifungal therapy.

Serious undesirable effects appear linked to the cumulative exposure to mitotane and are most likely to occur when mitotane plasma levels are at 20 mg/ l or above.

ADCETRIS-induced peripheral neuropathy is typically an effect of cumulative exposure to this medicinal product and is reversible in most cases.

Within the 5-year follow-up, particular emphasis will be placed on assessing the effects of a cumulative exposure of at least 18 months.

Serious undesirable effects appear linked to the cumulative exposure to mitotane and are most likely to occur when mitotane plasma levels are at 20 mg/l or above.

A large prospective observational study has shown an association between an increased incidence of chronic kidney disease and cumulative exposure to atazanavir/ritonavir-containing regimen in HIV-infected patients with an initially normal eGFR.

Data from a six-month dog study of daily intravenous injections of up to 0.5 mg/kg (10 mg/m mifamurtide provide an 8- to 19-fold cumulative exposure safety margin for overt toxicity for the intended clinical dose in humans.

In order to guarantee an optimum level of protection for persons working in the vicinity of machinery, and to keep the cumulative exposure of persons working in the vicinity of several different items of mobile machinery and equipment as low as possible, technology that is currently available should be used to minimise emissions.

The identification of relevant currencies should be based on materiality considerations, rely on the net cumulative liquidity exposure identified and based on data collected over an extended and well-defined period of time.

Acceptable methodologies are not yet available to systematically look at aggregate exposure (from other sources such as home and workplace) or cumulative exposure (intake from all dietary sources of similarly-acting substances).