Translation of "Airway inflammation" in German

One study showed that nobiletin reduced airway inflammation of asthmatic rats.

Airway inflammation triggers the production of excess mucus.

In asthma patients who have higher levels of periostin, IL-13 appears to be a major contributor to their airway inflammation.

Chronic airway inflammation is initiated by a variety of causes.

Allergic airway inflammation was assessed in mouse models of acute asthma.

Studies demonstrate that airway inflammation develops even after limited exposure to cannabis smoke.

Nitrogen dioxide is associated with airway inflammation and damage, and should be maintained as low as possible.

5 NO2 rapidly forms in gas mixtures containing nitric oxide and O2, and NO2 may in this way cause airway inflammation and damage.

NO2 rapidly forms in gas mixtures containing nitric oxide and O2, and nitric oxide may in this way cause airway inflammation and damage.

The therapeutic effect of inhaled corticosteroids is considered to be the result of suppression of airway inflammation, but the airway effects of ICS in COPD are complex and the mechanism of action is not completely understood (Finney et al., 2014, Jen et al., 2012).

Common side effects (may affect up to 1 in 10 people): - Fall in blood pressure - Breathlessness, noisy breathing (a high pitched sound resulting from obstructed air flow in the upper airway) - Rash and inflammation of the lining of the mouth, itching, itching rash, hives - Kidney problems which may be detected primarily by blood tests - Redness of upper body and face, inflammation of a vein Uncommon side effects (may affect up to 1 in 100 people): - Temporary or permanent loss of hearing

Airway inflammation below the vocal cords can cause narrowing of the trachea, leading to a hoarse voice, nosebleeds, chronic ear inflammation mimicking infection), and respiratory problems.

Authors wrote that their “findings indicate a protective role of CB1 receptors in airway inflammation.”

The present invention encompasses the use of the compounds of the formula I and/or physiologically acceptable salts thereof for the preparation of a medicament for the treatment or prevention of chronic obstructive pulmonary disease, anaphylactic shock fibrosis, psoriasis, allergic diseases, asthma, stroke, ischaemic states, ischemia-reperfusion, blood platelet aggregation or activation, skeletal muscle atrophy or hypertrophy, leukocyte recruitment in cancer tissue, angiogenesis, invasion metastasis, in particular melanoma, Karposi's sarcoma, acute and chronic bacterial and viral infections, sepsis, transplant rejection, graft rejection, glomerulosclerosis, glomerulonephritis, progressive renal fibrosis, endothelial and epithelial injuries in the lung, and lung airway inflammation.

The compounds of the formula (I) are preferably suitable for the treatment of chronic obstructive pulmonary disease, anaphylactic shock fibrosis, psoriasis, allergic diseases, asthma, stroke, ischaemic states, ischemia-reperfusion, blood platelet aggregation or activation, skeletal muscle atrophy or hypertrophy, leukocyte recruitment in cancer tissue, angiogenesis, invasion metastasis, in particular melanoma, Karposi's sarcoma, acute and chronic bacterial and viral infections, sepsis, transplant rejection, graft rejection, glomerulosclerosis, glomerulonephritis, progressive renal fibrosis, endothelial and epithelial injuries in the lung, and lung airway inflammation.

The compounds of the formula I are preferably suitable for the treatment of chronic obstructive pulmonary disease, anaphylactic shock fibrosis, psoriasis, allergic diseases, asthma, stroke, ischaemic states, ischemia-reperfusion, blood platelet aggregation or activation, skeletal muscle atrophy or hypertrophy, leukocyte recruitment in cancer tissue, angiogenesis, invasion metastasis, in particular melanoma, Karposi's sarcoma, acute and chronic bacterial and viral infections, sepsis, transplant rejection, graft rejection, glomerulosclerosis, glomerulonephritis, progressive renal fibrosis, endothelial and epithelial injuries in the lung, and lung airway inflammation.

Tobias Polte and his team from the Department of Environmental Immunology at the Helmholtz Centre for Environmental Research (UFZ) collaborated with Jan Simon and his colleagues from the Clinic for Dermatology, Venereology and Allergology at the University of Leipzig and have recently been successful in discovering a molecule that plays a significant role in the development of allergic airway inflammation – as demonstrated in their recent publication in Nature Communications.

A compound of any one of claims 1 to 16, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition of claim 17 for use in a method of treating a CXCR2-mediated disease or condition in a subject in need thereof, said method comprising administering an effective amount of the compound, or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition to said subject, wherein said CXCR2-mediated disease or condition is selected from the group consisting of psoriasis, rheumatoid arthritis, radiation induced fibrotic lung disease, autoimmune bullous dermatosis (AIBD), chronic obstructive pulmonary disease, and ozone-induced airway inflammation.

A method of treating a disease or disorder selected from the group consisting of psoriasis, rheumatoid arthritis, radiation induced fibrotic lung disease, autoimmune bullous dermatosis (AIBD), chronic obstructive pulmonary disease, and ozone-induced airway inflammation in a subject in need thereof, said method comprising administering an effective amount of a compound or a pharmaceutically acceptable salt of claim 1 to said subject.

The study credits this powerful anti-inflammatory enzyme with sneeze guard capabilities, meaning it lessened airway inflammation and stuffed sinuses in mice.

Measuring ECP in a serum sample is an objective and direct way of estimating the severity of the airway inflammation and following the course of the disease.

Asthma attacks (or exacerbations) are episodic, but airway inflammation is chronically present.

With its Departments of Clinical Airway Research and of Biomarker Analytics and Development, several clinical challenge models (e.g. normobaric hypoxia challenge) have been successfully implemented during recent years and non-invasive methods for monitoring of airway inflammation and systemic metabolism have been established.

Corticosteroids and bronchodilators, for example, are commonly employed to reduce airway inflammation and dilate the airway passage to facilitate breathing, respectively.

Subpopulations of Dendritic cells (DCs) and Regulatory T cells (Tregs) are considered to be protective during allergic airway inflammation.

In a recent example, the existence of an axis intestino-lung was suggested by a study that looks into a mouse model with an allergic inflammation of the Airways that a high fiber diet reduced airway inflammation while a low-fiber diet emphasizes a.