Übersetzung für "Tetanus toxin" in Deutsch

Tetanus toxin is another protein-neurotoxin produced by Clostridium tetani.

Then, the tetanus toxin blocks neurotransmitter release, and leads to muscular contractures and spasms.

The vaccine also contains a tetanus toxoid which is a tetanus toxin processed in order to decrease its toxic effect, but retain its antigenic power.

It is, of course, possible within the context of the present invention also to use other macromolecular compounds as carrier molecules provided that they fulfil the abovementioned requirements, such as porcine thyroglobulin, B2 microglobulin, haemocyanin, immunoglobulins, toxins (cholera, tetanus, diphtheria toxin, etc.), polysaccharides, lipopolysaccharides, natural or synthetic polyadenyl and polyuridyl acids, polyalanine and polylysine polypeptides or cell-membrane components, for example formalin- or glutaraldehyde-treated erythrocyte cell membranes.

The determination of tetanus antibodies is based on that a determined amount of tetanus toxin is mixed with different amounts of tetanus antitoxin-containing samples and injected in mice after previous incubation.

Tetanus is easily prevented by vaccination with an inactivated form of the toxin, tetanus toxoid, which induces neutralizing antibodies.

Treatment includes antibiotics and antibodies (proteins which fight infection) against the tetanus bacteria and the tetanus toxin.

The acute toxicity of this substance is exceeded only by very few natural substances. In animal tests the diptheria toxin proves to be three times as toxic, tetanus toxin 10,000 times as toxic, and the botulinum toxin A 30,000 as toxic as TCDD.

Many other species of Clostridia (perfringens, novyi, septicum, histolyticum, sordelli, aerofoetidum, tertium, sporogenes, etc) produce toxins similar to tetanus toxin as well as many other toxins.

As the carrier substances for a cyclization of this kind, all customary pharmaceutically applicable substances are eligible, which are able to covalently bind to the SH groups of the cysteins, for example (or to other naturally present or artificially introduced chemically reactive groups of the peptides); hereby, the customary carrier proteins such as keyhole limpet hemocyanine (KLH), tetanus toxin etc. are particularly preferred.

Your Message: I`m interested in your product: Tetanus toxin (antitoxin) IgG(Catno: EIA-3514)

Tetanus is treated with antibiotics and antibodies (proteins which fight infection) against the tetanus bacteria and the tetanus toxin.

It is, of course, also possible within the scope of the present invention to use other macromolecular compounds as carrier molecules as long as they meet the abovementioned requirements, such as, for example, porcine thyroglobulin, B2 microglobulin, hemocyanin, immunoglobulins, toxins (cholera, tetanus, diphtheria toxins etc.), polysaccharides, lipopolysaccharides, natural or synthetic polyadenylic and polyuridylic acids, polyalanyl and polylysine polypeptides or cell membrane components such as, for example, formalin- or glutaraldehyde-treated erythrocyte cell membranes.

The strongest toxins include e.g. the tetanus and botulinum toxins (botox), already toxic when only a thousandth of a gram is administered.