Übersetzung für "Metastasizing" in Deutsch

Fragments of the transplantable and metastasizing pancreatic adenocarcinoma CA20948 from rats were explanted from donor animals.

For example, on the surface of metastasizing tumor cells (Coggin et al., 1999;

In particular, growth and metastasizing of tumors can be determined.

He demonstrates his particular approach in the case of a metastasizing Ewing's sarcoma.

In addition to this, the compounds have an effect on tumor cells by preventing these cells from metastasizing.

Like metastasizing cancer cells, embryonal cells are capable of migrating and penetrating into other tissues.

But aggressive follow-up therapy will be required to prevent the remaining Al Qaeda cells from metastasizing by acquiring more adherents who believe in violence to achieve the 'purification' and empowerment of Islam.

It has been demonstrated that this vCD44 glycoprotein imparts metastasizing qualities to a tumor which, a prior, does not metastasize, whereas the standard type CD44 (sCD44) is not capable of this.

For this purpose, monoclonal antibodies (mAbs) were prepared which recognize the antigenic determinant on the metastasizing variant BSp73ASML.

It was thus clear to those skilled in the art that poly- or monoclonal antibodies which specifically recognize these epitopes, i.e. this additional extracellular region on various splicing variants of vCD44 and react therewith, and which may be labelled with radioisotopes and/or conjugated with cytocidal or cytotoxic substances, may be used for diagnostic and therapeutic purposes in the treatment of metastasizing tumors in humans (see PCT WO 91/17248).

Included in these are, for example, hyperproliferative diseases of the skin (psoriasis, pityriasis subia pilasis, acne, ichthyosis) as well as tumor diseases and precancerous stages (for example, tumors of the intestines, carcinomas of the breast, lung tumors, prostate carcinomas, leukemias, T-cell lymphomas, melanomas, Batazell Larzin, squamous carcinoma, actinic keratoses, cervix dysplasias, and metastasizing tumors of any type).

Included in these are, for example, hyperproliferative diseases of the skin (psoriasis, pityriasis subia pilasis, acne, ichthyosis) and pruritus, as well as tumor diseases and precancerous stages (for example, tumors of the intestines, carcinomas of the breast, lung tumors, prostate carcinomas, leukemias, T-cell lymphomas, melanomas, Betazell carcinoma, squamous carcinoma, actinic keratoses, cervix dysplasias, and metastasizing tumors of any type).

The functional inactivation of TSG 101 in fibroblasts leads to cellular transformation and to the ability to form metastasizing tumors.

Therefore, the development of further uPA inhibitors is very beneficial for further elucidating the role of uPA and uPAR in various diseases, especially in tumor spreading and metastasizing.

The compounds of the invention are capable of very effectively inhibiting the growth or/and spreading of malignant tumors, for example tumor spreading of pancreatic carcinoma, tumor growth of breast carcinoma and also metastasizing of tumors.

They are, for example, capable of very effectively inhibiting the growth or/and spreading of malignant tumors and also metastasizing of tumors.

The pharmaceuticals are preferably suitable for the prophylaxis and/or therapy of diseases which proceed with involvement of inflammatory processes, preferably of myocardial infarct and ischemia, post-infarct syndrome, shock lung of the adult, septic shock, stroke, acute and chronic organ rejection, vasculitis, inflammatory diseases of the skin, rheumatoid arthritis, restenosis after angioplasty and also metastasizing tumors.

Tumor cells which can be detected with the present invention are, in particular, tumor cells from metastases, preferably micrometastases, from malignant tumors, especially cells from metastasizing tumors and/or neoplasms which are derived, for example, from a T-cell lymphoblastoma, T-cell leukemia cells, chronic myeloid leukemia cells, acute lymphatic leukemia cells, chronic lymphatic leukemia cells, teratocarcinoma, melanoma, carcinoma of the lung, large bowel cancer, breast cancer, hepatocellular carcinoma, kidney tumor, adrenal tumor, prostate carcinoma, neuroblastoma, brain tumor, small-cell carcinoma of the lung, rhabdomyosarcoma, leiomyosarcoma and/or lymphoma.