Translation of "Gene transcription" in German

They bind to the DNA and help initiate a program of increased or decreased gene transcription.

Zoom Image Changes in gene transcription upon heat shock in human cells.

The laboratory of Patrick Cramer investigates the molecular mechanisms and systemic principles of gene transcription in eukaryotic cells.

These conditions are frequently caused by mutations that over-activate intracellular signalling or gene transcription.

In Alphaproteobacteria, methylation of adenine regulates the cell cycle and couples gene transcription to DNA replication.

The E. coli ATG expression vector pKK233-2 (trc-promoter, NcoI-PstI-HindIII polylinker, rrnB fragment with the 5S-rRNA gene and the transcription terminators T1 and T2) is obtained from the LKB Pharmacia company (Uppsala).

The bioB gene is therefore expediently the first gene within the transcription unit, because optimal expression of this gene can take place because of the vicinity to the promoter (FIGS.

This plasmid contains the tac promoter together with the bioB, bioF, bioC genes and complete bioD gene in a transcription unit (FIG.

Said transcription factor is either added to the cell culture medium, or the gene encoding the transcription factor is present on a plasmid in the cell, either in an integrated or non-integrated form, and is under the control of an inducible promoter.

For example, the gene encoding the transcription factor gene is selected from the group comprising zinc finger genes, pou genes, homeobox-containing genes, HGM-box-containing genes or winged helix genes.

Primary transcription factors are not first formed by the activation of the associated gene and subsequent transcription and translation.

The term “antisense molecule” or “antisense nucleic acid” refers according to the invention to an oligonucleotide which is an oligoribonucleotide, oligodeoxyribonucleotide, modified oligoribonucleotide or modified oligodeoxyribonucleotide and which hybridizes under physiological conditions to DNA comprising a particular gene or to mRNA of said gene, thereby inhibiting transcription of said gene and/or translation of said mRNA.

The term “antisense molecule” or “antisense nucleic acid” refers according to the present technology to an oligonucleotide which is an oligoribonucleotide, oligodeoxyribonucleotide, modified oligoribonucleotide or modified oligo-deoxyribonucleotide and which hybridizes under physiological conditions to DNA comprising a particular gene or to mRNA of said gene, thereby inhibiting transcription of said gene and/or translation of said mRNA.

As during this process the entire carrier structure is incorporated into the gene, transcription and the protein synthesis resulting are no longer possible.

In contrast, the addition of methyl groups (methylation) to some regulatory regions of the DNA itself reduces gene transcription.

Acetylation of histones reduces the positive charge on histone, reducing its interaction with the negatively charged phosphate groups of DNA, making it less tightly wound to DNA and accessible to gene transcription.

This gene is required for the morphogenesis of the urogenital system and represents a regulation gene for the transcription of the SRY.

Aaron Ciechanover, Avram Hershko and Irwin Rose furthered this understanding in more recent research, which showed the possibility of cell cycle control to change certain biological processes, such as gene transcription and immune function.

When mice with SETD5 mutation are set a learning challenge, the dynamics of gene transcription is different from that in mice without the mutation.

As co-transcription factors, the two proteins bind to certain transcription factors to regulate gene transcription, the process by which genetic information is copied from DNA to RNA to ultimately result in specific protein formation.