Übersetzung für "Overactivation" in Deutsch

The overactivation is easily apparent in the body.

Accordingly, overactivation of calpains can also initiate pathophysiological processes.

The immunosuppression is mainly mediated by an overactivation of the SNS.

Strengthens intestinal immunity and reduces immune system overactivation (allergies, inflammatory diseases).

And why is overactivation of STAT5B "good" for the tumor cell?

Sustained overactivation of the stress hormone system is usually the cause of this.

This heterogeneity could be counteracted by overactivation of maintained cell cycle mechanisms which are common to many types of tumour cell.

Overactivation of mTOR results in neuronal dysplasia, aberrant axonogenesis and dendrite formation, increased excitatory synaptic currents, reduced myelination, and disruption of the cortical laminar structure causing abnormalities in neuronal development and function.

Mutations in the tumour suppressor protein APC (adenomatous polyposis coli) occur in about 80 percent of all intestinal tumours, leading to the overactivation of the Wnt signalling pathway.

Overactivation of src, however, such as by mutation, can lead to increased activity of src, which can cause overgrowth and malignancy of cells.

This substance causes an overactivation of the neurotransmitter NMDA, which may participate in the onset and development of neurological disorders.

Left untreated, this overactivation can also lead to possible secondary diseases such as high blood pressure, heart attack, stroke, diabetes and osteoporosis.

Overactivation of PARP would accordingly result in a nonphysiologically large consumption of ATP, and this leads in the extreme case to cell damage and cell death.

Overactivation of PARP would accordingly have resulted in an unphysiologically high consumption of ATP and this leads, in extreme cases, to cell damage and cell death.

This in turn results, in principle, in a more favourable pharmacological safety profile compared to agonists, since toxic effects caused by receptor overactivation are limited (Christopoulos, Mol.

This in turn results, in principle, in a more favorable pharmacological safety profile compared to agonists, since toxic effects caused by receptor overactivation are limited (Christopoulos, Mol.

Overactivation of MAP kinase signalling leads to dedifferentiation features of epithelial-to-mesenchymal transition (EMT).

The genetic risk map of chronic inflammatory bowel disease (IBD) with its two subentities Crohn´s disease (CD) and ulcerative colitis (UC) has elucidated a crucial role for the intestinal epithelium in addition to a chronic overactivation of immune cells.

An investigation of the amygdala in these animals revealed that the overactivation of the amygdala was normalized, and that this effect resulted from a strengthening of the synaptic transmission at inhibitory synapses in the amygdala.

Science/Animal: Overactivation of the CB1 receptor in certain kidney cells fastens kidney damage in type 2 diabetes Research with diabetic rats shows that increased activation of the CB1 receptor in certain kidney cells – so-called podocytes – contributes to the development of kidney damage in diabetes, "highlighting the therapeutic potential of peripheral CB1 receptor blockade."

Suppressor of cytokine signaling-3 (SOCS3): Expression of SOCS3 is also stimulated by leptin and this negative feedback mechanism prevents overactivation of leptin-signaling pathways.

This is because overactivation of Ras is carcinogenic: in around a third of cancer patients, the Ras proteins of cancer cells are mutated, resulting in uncontrolled cellular division.

The disturbed control system for stress hormones is the cause as persistent overactivation of the stress hormone system can disturb nerve cell metabolism to such a degree that the production and degradation of the transmitters is derailed.