Übersetzung für "Nanomolar" in Deutsch

This also permits small synthesis mixtures in the nanomolar to picomolar range to be carried out.

Result: pepstatin inhibits cathpsin D in the nanomolar range (see Table 1).

Four of them inhibited the enzyme in the nanomolar range.

Indacaterol is a partial agonist at the human beta2-adrenergic receptor with nanomolar potency.

The developed YC-Nano Ca2+ biosensors were able to detect nanomolar changes of Ca2+ concentrations.

In contrast thereto, rapamycin is active in inhibiting the proliferation of SMC cultures in the nanomolar concentration range.

Pepstatin exhibits an IC 50 value in the nanomolar range in the GAG assay (see Table 1).

Roflumilast targets the PDE4A, 4B and 4D splicing variants with similar potency in the nanomolar range.

Farydak is a histone deacetylase (HDAC) inhibitor that inhibits the enzymatic activity of HDACs at nanomolar concentrations.

Neuraminidase inhibition occurred at very low peramivir concentrations in-vitro, with median inhibitory concentration 50% (IC50) values of 0.13 nanomolar (nM) to 0.99 nM against influenza A and B strains.

Inhibition of mTOR activity results in a G1 growth delay at nanomolar concentrations and growth arrest at micromolar concentrations in treated tumour cells resulting from selective disruption of translation of cell cycle regulatory proteins, such as D-type cyclins, c-myc, and ornithine decarboxylase.

Mepolizumab inhibits the bioactivity of IL-5 with nanomolar potency by blocking the binding of IL-5 to the alpha chain of the IL-5 receptor complex expressed on the eosinophil cell surface, thereby inhibiting IL-5 signalling and reducing the production and survival of eosinophils.

Fingolimod phosphate binds at low nanomolar concentrations to sphingosine 1-phosphate (S1P) receptor 1 located on lymphocytes, and readily crosses the blood-brain barrier to bind to S1P receptor 1 located on neural cells in the central nervous system (CNS).

The affinity of L-RNA aptamers to their target molecules often lies in the pico to nanomolar range and is thus comparable to antibodies.

However, the kinetic boundary conditions of a chemical detecting reaction which is to proceed in the seconds to minutes range for practicability require the use of labeled detector reagents in excess over an analyte in the nanomolar range and above.

In assays of this type, the compounds according to the invention preferably exhibit and cause an inhibiting effect, which is usually documented by IC 50 values in a suitable range, preferably in the micromolar range and more preferably in the nanomolar range.

Thanks to the SCONP principle (see also image 2), beginning with the complex natural product yohimbine, indoloquinolizidines and the indole matrix were chosen as the starting point for libraries 3 and 4.These libraries then led to nanomolar inhibitors of the phosphatase MptpB and Ptp1B at low, micromolar scales.

Many of the most important clinical-diagnostic analytes are only inexpensive and quickly measurable with immunoassays as there are no alternative analytical chemical methods offering an equivalent combination of high sensitivity (detection of nanomolar or lower concentrations) and high specificity (detection of the analyte in the presence of interfering substances with a chemically similar structure).

However, typical immunoassay analytes have to be measured in the nanomolar concentration range (or lower), i.e., a million times more sensitive.