Übersetzung für "Evidenzgrad" in Englisch

The CHMP concluded that the level of evidence provided is limited.

The degree of evidence of the treatments listed is variable.

The evidence level of the study is named that leads to the corresponding recommendation level.

Thus, the level of evidence reached for penile cancer based on the literature is consistently low.

Although the level of evidence is limited, the CHMP recognised that in selected cases and at the discretion of the treating physician the addition of mitoxantrone to combination regimens could be of benefit to this patient population, and accepted the indication.

The CHMP considered the level of evidence currently available insufficient to support the use of mitoxantrone in hepatocellular carcinoma, which the MAH accepted and therefore withdrew this indication from the proposed harmonised PI.

With regard to endovascular operations, at least studies with larger patient numbers do exist (Neglén et al., n = 982), meaning that evidence level B is attained (22).

It was found in a randomized controlled trial of combination therapy to prevent relapses in adolescents that the risk of a relapse was significantly lower if CBT was given for 36 weeks than if fluoxetine was continued without any accompanying CBT (evidence level 3; this RCT did, however, have certain methodological flaws [e25]).

The administration of single agents or less intensive combinations should therefore be omitted as a rule (A).

In the case of contraindications to cisplatin, the use of alternative protocols is preferable in any case to an abstention from adjuvant chemother- apy (A).

The AHA gives a weak recommendation for endovascular treatment (recommendation class IIb, evidence level B) (17).

For this reason the AHA recommends a supervised exercise program (recommendation class IIa, evidence level B) (17).

A switch from outpatient treatment to day hospital care or to inpatient treatment can also be considered, according to the recommendations of this guideline (evidence level 5, open recommendation, strong consensus).

Numerous controlled (open and blind) researches having a level of evidence compliant with the university standard that were conducted using animal and plant models in international institutes (in university and government-aided institutes to a large extent) document the biological effectiveness of the classic bioresonance method.

The analysis revealed a lower level of evidence for psychodynamic or systemic psychotherapy or for drug treatment with escitalopram, citalopram, or sertraline.

Controlled randomized clinical studies and meta-analyses are the favoured information sources of the EBM, though, in case no better information is on hand, also findings of lower evidence level are explicitly permissible.

According to the DGP guidelines, intermittent pneumatic compression improves the symptoms of severe postthrombotic syndrome (evidence level B) (14).

Likewise, the prolongation of CBT for a further six months after ten weeks of acute treatment has been found to be associated with a lower cumulative risk of relapse than management in a control group (evidence level 4 [e18]).

Nor should paroxetine, venlafaxine, or mirtazapine be given to children and adolescents with depressive disorders, as these have not been found any more effective than placebo but are associated (particularly venlafaxine) with increased suicidality (evidence level 1 [e4], strong recommendation, recommendation grade A).

For instance, 77 to 98% of patients with anti-NMDA receptor encephalitis are able to live independently by 2 years after diagnosis (multicenter observational study with 577 patients, evidence level III) (28).

Systematic reviews (SRs) with quantitative analyses (meta-analysis) of randomized clinical trials (RCTs) and overviews of SRs have the highest level of evidence in evidence-based medicine (3).

If treatment with fluoxetine is not possible or not desired, escitalopram, citalopram, and sertraline are recommended as alternative drugs (recommendation grade B, evidence level 1 [e4, e9]).

Based on the existing small studies, the AHA can only give a weak recommendation for the use of these bypasses (recommendation class IIb, evidence level C) (17).

The "all-or-none principle" (level of evidence Ic) allows for the classification of medical interventions that make an integral part of routine medical care without the requirement of relevant studies on hand because they cannot be conducted for ethical reasons (e.g. oxygen insufflation for hypoxia).