Translation of "Verzögerungsinsulin" in English

Designations used synonymously for long-acting insulins are slow insulins, depot insulin or else basal insulin.

Mixed insulins consist of a rapid-acting insulin and an extended-acting insulin in various mixing ratios.

Administer your usual delayed-action insulin on the day of your departure.

Upon arrival, skip your first regular injection of delayed-action insulin.

Long-acting insulin provides little flexibility.

Do not resume your normal rhythm until after you administer your second injection of delayed-action insulin adjusted to the local time.

For slow acting insulin (insulins with delayed action or mixed insulins) the recommended injection site is:

If the therapeutic regimen requires the injection of basal insulin and Insulin lispro Sanofi at the same time, the two can be mixed in the syringe.

If the therapeutic regimen requires the injection of basal insulin and Liprolog at the same time, the two can be mixed in the syringe.

The CHMP concluded that combination treatments with a long-acting insulin and a GLP-1 agonist such as Suliqua are an important treatment option for patients who are eligible for insulin or who need intensive insulin therapy.

The second study involved 736 patients whose blood glucose was not adequately controlled by a longacting insulin such as insulin glargine with or without one or two other diabetes medicines taken by mouth.

It is used when blood glucose (sugar) levels are not satisfactorily controlled by metformin alone or by a combination of metformin and another medicine (either another glucose-lowering medicine taken by mouth or a long-acting insulin).

Bydureon is a diabetes medicine used together with other diabetes medicines including long-acting insulin to treat adults with type 2 diabetes whose blood glucose (sugar) levels are not adequately controlled with the other medicines.

The fourth study (in 456 patients) compared Bydureon with insulin glargine (a long-acting insulin) as add-on treatment to metformin with or without a sulphonylurea.

If the therapeutic regimen requires the injection of basal insulin and Humalog at the same time, the two can be mixed in the syringe.

Also conceivable are so-called slow release formulations in which the slow insulin of the invention is present reversibly bound to a polymer carrier.

The invention further relates to a process for preparing the insulin analogues of the invention, where a precursor of the insulin analogue is prepared recombinantly and converted enzymatically into a two-chain insulin precursor which carries arginine or lysine N-terminally in relation to amino acid 1 of the A chain, and has at the C-terminal end of the B chain a lysine or arginine residue which is converted with argininamide or lysinamide in the presence of an enzyme having trypsin activity into the amide and thus into the slow insulin of the invention, and is prepared with high purity by a biochemical purification process.

It will be clear to a skilled worker in this connection that appropriately formulated mixtures of fast-acting and slow insulin of the invention can also be used for this purpose.

In this case, a basic supply is ensured with an extended-action insulin (basal) and a rapid-acting insulin (bolus) is given additionally at meal times.

This is caused by changes in insulin requirements during the night, which are unable to be adequately covered with long-acting, delayed-action insulin.

It is difficult to manage irregular daily routines and shift work with long-acting insulin because the basic insulin requirements are constantly fluctuating.

A long-acting insulin (“basal insulin” or “delayed-action insulin”) is injected once or twice a day in order to meet the body's basic requirements.

Insulin therapy The standard treatment consists of intensified conventional therapy [ICT] with a basal or delayed insulin preparation to cover mealtimes and to correct elevated glucose values, with an individualized schedule for each child or adolescent patient (13).

People performing this kind of therapy need an intensive training. They have to check blood glucose levels 4 -7 times a day, keep an accurate diary and they need to be willing to inject insulin several times a day.