Translation of "Pluripotenz" in English

However, the cells quickly lost their pluripotency.

Is it now possible to induce pluripotency via small molecules?

Reliable proof of pluripotency is based on various tests:

Down regulation of Oct3/4 levels are associated with loss of pluripotency.

The gold standard of pluripotency is the embryonic stem cell (ESC).

Thereby the cells specify themselves initially but retain their pluripotency.

Important transcription factors that can induce and preserve pluripotency were discovered in the course of this research.

What molecules are responsible for pluripotency and how they can be administered without any side effects?

This ability is called totipotency and is comparable with the pluripotency of animal ES.

The myotomes have not lost their pluripotency though, as has been shown using transplantation experiments on chicken embryos.

One of the objectives of the project is to research pluripotency with a view to therapeutic applications.

Embryonic stem cells have occupied center stage, chiefly because of their pluripotency -- that is their ease in differentiating into a variety of different cell types.

Embryonic stem cells have occupied center stage, chiefly because of their pluripotency -- that is their ease in differentiating into a variety of different cell types.

Besides actively regulating gene expression, dynamic remodeling of chromatin imparts an epigenetic regulatory role in several key biological processes, egg cells DNA replication and repair; apoptosis; chromosome segregation as well as development and pluripotency.

A German-British team of scientists has now discovered human endogenous retrovirus H (HERVH) viruses that play a role at a very early stage of the development of pluripotency.

Sometimes, however, they fail to provide irrefutable proof of the pluripotency of the reprogrammed cells – even when the corresponding results have been published in prestigious scientific journals.

The previous image of a strong, self-regulating core pluripotency network of the factors Nanog, Oct4 and Sox2 has thus been refuted.

Therefore, stable pluripotency in the adult organism is something special but not impossible as long as mechanisms exist for conserving this characteristic – as is clearly the case with the planarians.

To this end, different methods of reprogramming (integrating and non-integrating) as well as several options for characterisation of pluripotency have been established.

In healthy mammals, pluripotency, that is the ability of one cell to produce any given cell type found in an organism, e.g. muscle, nerve or pancreas cells, only arises in the early embryonic stage.

This consists of transferring genes responsible for pluripotency in stem cells in order to change somatic, specialized cells into undifferentiated cells, the so-called induced pluripotent stem cells.

The preservation of pluripotency has been an important topic in stem cell research for years, and has mostly been examined up to now using isolated embryonic stem cells.

Identifying the factors that are decisive for embryonic cloning and pluripotency will be the subject of future research.”