Translation of "Heterozygosity" in German

The positive correlation between UV-reflection and individual heterozygosity supports this view.

This is the technical explanation for the somewhat strange term "loss of heterozygosity".

Namely, if two or more subpopulations have different allele frequencies then the overall heterozygosity is reduced, even if the subpopulations themselves are in a Hardy-Weinberg equilibrium.

Preclinical studies indicated that the thiocolchicoside metabolite 3demethylthiocolchicine (M2, SL59.0955) may be associated with aneuploidy (abnormal chromosome number and loss of heterozygosity) in dividing cells, at levels of exposure not much greater than those achieved in the body with maximum recommended oral doses.

Prior to unblinding of the study, tumours of patients were tested for the presence of HRD using an experimental HRD test, which evaluates three indirect measures of tumour genome instability: loss of heterozygosity, telomeric allelic imbalance (TAI), and large-scale state transitions.

The heterozygosity of the total population is then given by the mean of the heterozygosities of the subpopulations, weighted by the subpopulation size.

If the patient is supposed to be homozygous, testing the parents can yield further hints that are important for the human genetic assessment (isodisomy, hemizygosity, compound heterozygosity, etc.).

The genetic test showed a compound heterozygosity with nonsense mutation in exons 6 and 11 (heterozygous nonsense mutation in exon 6b (p.Q250X, apparently a very rare mutation) and in exon 11 (G542X)).

If two different alleles of a gene occur on the two chromosomes on the relevant gene locus, this is called heterozygosity.

In case of a compound heterozygosity in a future child of ours - what would be the consequences?

It is to ensure the maintenance or restoration of genetic diversity in the dog genome, that is based on heterozygosity.

But since the dog's genome has already been researched and it is known that heterozygosity is required, DNA-testing may be helpful for the exploration of certain inherited diseases and the nature of specific genes (MHC), which view the diversity in a special strain.

If two different alleles of a gene appear on the two chromosomes at the relevant gene locus, this is called heterozygosity.

They analysed the variability (i.e. homo- vs. Â heterozygosity) of a gene of the major histocompatibility complex (MHC), which has an important role in recognizing infectious agents.

Your case is therefore a combination of mutations with so-called heterozygosity (as opposed to homozygosity).

The compilation according to the invention and/or the method according to the invention therefore surprisingly allow an extremely reliable differential diagnosis in the case of obesity, in particular with respect to homozygosity and heterozygosity in the obesity gene which encodes leptin and mutated leptin respectively, at the protein level, in particular using an immunological test system or immunological test method.