Translation of "Autocrine" in German

It can have endocrine, paracrine, and autocrine effects.

Thus, tumour-derived VEGF does not function as an autocrine mitogenic factor.

It may also play an important role as an autocrine growth factor in metastatic prostate cancer.

Via the autocrine function, it affects cell differentiation, cell proliferation and immunomodulation.

This constitutive activation is controlled dynamically by Tie1 and in particular by autocrine-acting Ang2.

Endothelin-1 (ET-1) is a potent vascular paracrine and autocrine peptide in the lung, and can also promote fibrosis, cell proliferation, cardiac hypertrophy, and remodelling and is pro-inflammatory.

Mechanism of action Endothelin-1 (ET-1) is a potent vascular paracrine and autocrine peptide in the lung, and can also promote fibrosis, cell proliferation, cardiac hypertrophy, and remodelling and is pro-inflammatory.

One approach used by tumors to upregulate growth and survival is through autocrine production of growth and survival factors.

Following interaction with a cytokine, many cells produce more cytokines and release them, whereby the cells themselves can thus be stimulated or inhibited the (so-called autocrine mechanism).

The named autocrine factors and components for building the macromolecules of the extracellular cartilage matrix have molecular weights which are such that they cannot pass through a membrane with the named permeability.

A protein identified by Scientists named autocrine motility factor (AMF), that causes cancer cells to grow "arms" or pseudopodia, enabling them to migrate to other parts of the body.

Besides their metabolic importance inside cells, adenosine triphosphate (ATP) and other adenine nucleotides fulfill important roles outside of cells as autocrine and paracrine signal mediators.

In further experiments we investigated the involvement of voltage-gated sodium and calcium channels in the autocrine regulation of Müller cell volume.

As soon as cells detach from the epithelium, heregulin is able to contact its receptors, establishing an autocrine feedback loop stimulating proliferation.

They found that an autocrine endocannabinoid signalling might be operational during spermatogenesis, and that the ECS is modulated during meiosis, with the levels of the endocannabinoid 2-arachidonoylglycerol peaking before meiosis.

In addition, numerous peptidal growth factors have a paracrine or autocrine effect on the local metabolism in the various compartments of the gland, by means of which the equilibrium of the cell kinetics can be shifted between proliferation and programmed cell death.

Tumor cells themselves produce IL-6 which, in an autocrine mechanism, stimulates the growth and migration of the cells.

That's why intercellular ROS signaling goes both in the interaction between transformed and not-transformed cells (classical intercellular induction of apoptosis) and also in an autocrine manner between transformed cells (as shown in this illustration).

However, proliferation is comparable in the two mixtures, and thus the autocrine growth of the T cells must be attributed to other factors on costimulation of 8F4.

The named compounds are especially autocrine factors and substances serving as components for building the extracellular structure.

In cells, in which the CFTR function is not disturbed, it encroaches on an autocrine mechanism, which is steered by the release of and the signal transmission by ATP (adenosine triphosphate) through a separate ion channel.

Healthy blood cells react thereon with an autocrine signal-cascade, that is started by the CFTR dependent ATP release and leads to the delivery of osmolytes.

In addition, IGF-1, while integrally involved in the normal growth and differentiation of the nervous system, also appears to be an autocrine stimulator of human gliomas.

We aim investigating the role of several endocrine, autocrine and paracrine substances in the control of renal arteries and microvessels.