Übersetzung für "Pericytes" in Deutsch

The regenerative capacity of pericytes is affected by the host microenvironment.

Neuropathy is caused by hyperglycemia-induced apoptosis of pericytes in diabetic patients.

Pericytes are cells that wrap around endothelial cells throughout the body.

Pericytes have many different roles that contribute to the progression of ischemic strokes.

Pericytes can also be isolated from the cerebral cortex and reprogrammed into functional neurons.

Pericytes contribute to the formation of skeletal muscle.

Ang1 is secreted constitutively by pericytes and activates the Tie2 receptor localized on the endothelial cells.

Venules accompany arterioles, and have a structure similar to the capillaries, with contractile cells called pericytes.

In this project a 3-dimensional model of the blood-brain barrier was simulated using endothelial cells, astrocytes and pericytes.

The density of pericytes is highest, and they have several roles within the central nervous system microenvironment.

The disease is caused by the apoptosis of pericytes or their detachment from the basement membrane.

Back to overview Pericytes cells form, together with other cells a scar after a spinal cord injury.

In particular, treatment of tumour xenografts with nintedanib led to a rapid reduction in tumour micro vessel density, pericytes vessel coverage and tumour perfusion.

Nintedanib binds competitively to the adenosine triphosphate (ATP) binding pocket of these receptors and blocks the intracellular signalling which is crucial for the proliferation and survival of endothelial as well as perivascular cells (pericytes and vascular smooth muscle cells).

Histologically, flat preparations of the retinal blood vessels exhibit caliber fluctuations in the area of the vascular walls and a loss of pericytes and endothelial cells from the vascular walls.

We examine the signaling interplay between endothelial cells as well as interactions of endothelial cells with pericytes and tumor cells.

Glomus tumours are composed of specialized pericytes (glomus cells), blood vessels and smooth muscle cells, involving a glomeriform arteriovenous anastomosis (glomus body).

Furthermore, in vivo interaction between endothelial cells and other cells types (such as fibroblasts, pericytes and macrophages) is cumbersome to translate and simulate in vitro .

The stromal-vascular fraction in the pellet is composed of a heterogeneous cell population of blood cells, fibroblasts, pericytes, endothelial cells and preadipocytes.

These is an initial thickening of the basal membrane of the vessels and loss of vascularized pericytes, followed by vascular occlusion and retinal ischaemia.

Diabetic retinopathy is primarily caused by microvascular deficiency, which leads to basal membrane thickening of the vessels and loss of vascularized pericytes followed by vascular occlusion and retinal ischaemia which, owing to the retinal hypoxia thus caused, may lead to enhanced vessel permeability with subsequent formation of a macular oedema and, due to all of the processes present, to the patient going blind.

However, the blood brain barrier, which is composed of endothelial cells, pericytes and astrocytes and which seals the brain off from circulating particles, toxins and signal compounds, represents a barrier that cannot be passed by normal vector systems.